Showing posts with label science-ed. Show all posts
Showing posts with label science-ed. Show all posts

January 17, 2020

Work With Me in 2020


The Google Summer of Code (GSoC) is once again accepting applications from students to work on a range of programming-oriented projects over the Summer of 2020. Orthogonal Research and Education Laboratory and the OpenWorm Foundation have contributed a number of projects to the list. Here are links to the project descriptions (login to INCF Neurostars required):


DevoWorm Group:

Project  #15: OpenDevoCell Integration

Orthogonal Laboratory:


I am the contact person for both the Orthogonal Laboratory and DevoWorm Group projects. If you have any questions about the application process or want to have be review your application before submission, please feel free do so. According to this year's schedule, the proposal deadline is March 31, and the community bonding period starts on April 27. Stay tuned!

Join us once again on the "Road to GSoC"!

September 2, 2019

Introducing: DevoWormML

This has been cross-posted to The Node blog.


I am pleased to announce a new collaborative interest initiative called DevoWormML, based on work being done in the DevoWorm group. DevoWormML will meet on a weekly basis, and explore the application of machine learning and artificial intelligence to problems in developmental biology. These applications can be geared towards the analysis of imaging data, gaining a better understanding of thought experiments, or anything else relevant to the community.

While "ML" stands for machine learning, participation can include various types of intelligent systems approaches. Our goal is to stimulate interest in new techniques, discover new research domains, and establish new collaborations. Guests are welcome to attend, so if you know an interested colleague, feel free to direct them our way.

Meetings will be Wednesdays at 1pm UTC on Google Meet. Discussions will also take place on the #devowormml channel of OpenWorm Slack (request an invitation). We will discuss organizational details at our first meeting on September 4. If you cannot make this time but are still interested in participating, please contact me. Hope to see you there!

May 31, 2019

Summer of Working Groups


I am happy to announce that this Summer I will be advising/mentoring two research groups of Google Summer of Code (GSoC) students and applicants. Thanks to INCF for sponsoring our applications and applicants again this year. The first group (DevoWorm), based in the OpenWorm Foundation, is interested in image segmentation and Machine Learning. GSoC applicants Asmit Singh and Ujjwal Singh (currently attending IIT Delhi) are working on extracting quantitative data to construct a digital model for organisms in the diatom genus Bacillaria. The GSoC student (Vinay Varma, currently attending Amrita Vishwa Vidyapeetham University) is working on developing a method for Semantic Segmentation based on microscopy of the embryogenetic process, focusing on the biology of Caenorhabditis elegans.

The other group is based in the Orthogonal Research and Education Laboratory, and is focused on creating a methodology for developmental Braitenberg Vehicles. This involves simulating the formation of a brain (neurons and connectome) in a simple body that continuously interacts with its environment. The GSoC student in this group (Stefan Dvoretskii) is developing such a model using Genetic Algorithms and the open-source SimBrain platform. The GSoC applicants (Ziyi Gong, Jesse Parent, and Ankit Gupta) are working on a variety of unique approaches that will aid in our
understanding of this complex system. These alternative approaches range from biologically-inspired (Ziyi) to a cybernetic architecture based on the Every Good Regulator Theorem (Jesse).

The hybrid education/research working group is something I started with last year's Orthogonal Lab GSoC group. There is a good chance that this Summer's discussions and work periods will produce awesome, cutting-edge science. Follow us on Github (DW group, BV group) and YouTube (DW group, BV group) for more!

April 27, 2019

Open Leaders 7 is almost finished. Join us for a Sprint!





In a previous post, I mentioned that I was a part of Mozilla's Open Leaders program, which is dedicated to working open and improving the overall health of the internet. Each Open Leader worked on an open project over the duration of the 14 week program, which in my case is an open educational curriculum for the DevoWorm group and the OpenWorm Foundation more generally.

Purpose and Outcomes from the Mozilla's POP (purpose, outcomes, process) standards for project management). Click to enlarge.

The purpose of building this curriculum is twofold: to encourage contributions to the organization, and to create educational opportunities that enrich people's contributions. Therefore, our curriculum combines topical tutorials with course materials focused on interdisciplinary topics (bridging data science, computer science, and biology) and training in niche topical areas. The curriculum has a front-end (managed at Eliademy) and a back-end (managed in a Github repository). You can make contributions to the front-end by either enrolling in the course or making notes in hypothes.is.






Examples of the front-end, back-end, and course content. Click to enlarge.

Another way to contribute is to attend the Sprint for Internet Health. Last year this was referred to as the Global Sprint, and gives people an opportunity to engage in open source creation as well as consumption. Our project already has two contributors (Asmit Singh, Vinay Varma, and Uggwal Singh, who are also Google Summer of Code applicants to the organization) who have been refining the materials by way of pull requests. More details to come!

Details on how to get involved. Click to enlarge.

UPDATE (5/25): An interview with project lead Bradly Alicea (by Robert Schafer) is now available on the Mozilla Open Leaders Medium blog.


February 6, 2019

Mozilla Open Leaders 7


I have been selected into the Mozilla Open Leaders program as a cohort member. This is the seventh edition of the program (hence the abbreviation OL7), and runs for 14 weeks. During this time, I will learn how to better leverage digital tools for building online communities. I am working within the OpenWorm Foundation to apply these principles to a specific context.




The hashtag #WOLO also serves as the guiding principle of Open Leaders: work open, lead open. Open Leaders come from all walks of life, and all sorts of digital organizations. I am in cohort A, which is part of the project track. Together, we will work to improve the "health" of the internet.

May 21, 2018

Rise of the Alt-Research Program

It is time for a new paradigm! In the past 5 years or so, a new type of research institute has arisen [1]. One that is flexible and open, without the constraints typical of a University or corporate labs. In a time of institutional change and funding uncertainty, such institutes provide a means for many non-conventional types of research to flourish. We can think of such facilities an "Alt-research Program" (after the "alt-academic" movement) [2], although stressing the open science and collaborative aspects are also important. So let's discuss some recent developments for one such organization, Orthogonal Research and Education Laboratory.


We have three recent developments: a new paper collaboration, a preprint mention, and a set of Google Summer of Code presentations. First up is a paper that was recently published with three co-authors. Orthogonal Research is a nexus for open science-enabled collaborations with University-based academics [3]. The paper “Network Dynamics of Attention During a Naturalistic Behavioral Paradigm” is now live at Frontiers in Human Neuroscience [4]. Learn about the what happens in attentional networks of the human brain during naturalistic behavior – in this case, high-resolution video game play with neural activity captured via “free-viewing” neuroimaging.

Here is how you build institutional credibility (or so I've heard). Notice the second affiliation.

From Figure 3 in the paper (drawings courtesy of Dr. Richard Huskey).

Screen shot of the first-person video game stimulus "Tactical Ops: assault on terror". Screenshot courtesy of Top Full Games and Software.

Orthogonal Lab was also recently mentioned in a preprint on scientific ecosystems [5] from members of the Ronin Institute. In the paper, Orthogonal Lab was described as a lab focusing on more specific research questions than a larger institute focused on enabling basic science initiatives (such as Neurolinx). This new scientific ecosystem paradigm proposed in the paper is focused on how to enable collaboration and open science outside of the formal University structure.


Thirdly, we have community period [6] presentations by three students in this year’s Google Summer of Code program (sponsored by INCF). There will be a presentation now, and a final presentation at the completion of the Summer. The idea is to keep students thinking about the project's progress, to develop their public speaking/presentation skills, and to build up the foundations for a paper or future research. Cheng-Hsun (Jim) Hsueh and Sam Felder are working on Contextual Geometric Structures project (Representational Brains and Phenotypes Group), while Arnab Banerjee is working with the OpenWorm Foundation (DevoWorm Group).




One way to enable Alt-research Programs is to embrace low carbon and location-free modes of doing and disseminating research. One such proposal (by Dr. Angel Goni-Moreno) has been made to provide low-carbon and researcher-accessible conferencing options to the annual ALife conference. In particular, distributed sessions would enable participation and collaboration across continents and research groups that would otherwise not interact.

The new research ecosystem paradigm path to field-specific and interdisciplinary community-building?

NOTES:
[1] See a previous Synthetic Daisies post on hosting theory hackathons through such as organization.

[2] While I find the prefix "alt-" to be a shallow marketing term (sometimes nefariously so), it does fit into existing descriptions of academic activity outside of or in parallel with Universities.

[3] The two main collaborators were the Media Neuroscience Laboratory at UCSB and the Cognitive Communication Science Laboratory at OSU.

[4] Here are the essential materials: Paper, Supplemental Materials, Open Dataset, Video Game Stimulus.

[5] Lancaster​​, A.K., Thessen​, A.E., Virapongse​, A. (2018). A new paradigm for science: nurturing the ecosystem. doi: 10.7287/peerj.preprints.26885v2.

[6] Typically, the community period is an opportunity for students to get acquainted with the community resources (open datasets, open codebase, community members) of their chosen open source/science organization. For more information on the Google Summer of Code community period, here are a few blog posts (1, 2, 3, 4, 5).

March 19, 2018

Google Summer of Code Application Deadline is Approaching!


A quick reminder as to what is near. Nothing to fear -- except that applications for Google Summer of Code 2018 are due on March 27th (in a little more than a week). Thanks to all the applicants to our projects so far. I am the mentor for the following projects (all sponsored by INCF):

Contextual Geometric Structures (Project 8)

Towards a k-D embryo (Project 10.2)

Physics-based XML (Project 10.1)

Apply to work work either the Orthogonal Research Lab community (Project 8) or the OpenWorm Foundation community (Projects 10.1, 10.2). Please contact me (Bradly Alicea) for more information.

There are several other projects hosted by the OpenWorm Foundation that combine work with Neuroscientific data and Computational Modeling. These include:

Advanced Neuron Dynamics in WormSim (Project 10.3)

Mobile application to explore C. elegans nervous system dynamics (Project 10.4)

Add support for Neurodata Without Borders 2.0 to Geppetto (Project 10.5)

All three of these projects are based in the OpenWorm Foundation community, and are lead by mentors Matteo Cantarelli, Giovanni Idili, and Stephen Larson.

December 15, 2017

Work With Me, the Orthogonal Laboratory, and the OpenWorm Foundation This Summer!


The Google Summer of Code (GSoC) is once again accepting applications from students to work on a range of programming-oriented projects over the Summer of 2018. Orthogonal Laboratory and the OpenWorm Foundation have contributed a number of projects to the list. Here are links to the project descriptions (login required):

Orthogonal Laboratory:


DevoWorm Group:



OpenWorm Foundation:



I am the contact person for the Orthogonal Laboratory and DevoWorm Group projects, and Matteo Cantarelli is the contact person for the other projects. If you have any questions about the application process or want to have be review your application before submission, please feel free do so. The deadline for application submission is tentatively in late March/early April. Stay tuned!

Join us on "The Road to GSoC"!


September 11, 2017

This Concludes This Version of Google Summer of Code


I am happy to announce that the DevoWorm group's first Google Summer of Code student has successfully completed his project! Congrats to Siddharth Yadav from IIT-New Delhi, who completed his project "Image Processing with ImageJ (segmentation of high-resolution images)".

Our intrepid student intern

His project completion video is located on the DevoWorm YouTube channel. This serves as a counterpart to his "Hello World" video at the beginning of the project. The official project repo is located here. Not only did Siddharth contribute to the data science efforts of DevoWorm but also contributed to the OpenWorm Foundation's public relations committee.

Screenshot from project completion video

As you will see from the video, a successful project proceeds by organizing work around a timeline, and then modifying that timeline as roeadblocks and practical considerations are taken into account. This approach resulted in a tool that can be used by a diverse research community immediately for data extraction, or build upon in the form of future projects. 

In terms of general advice for future students, communicate potential problems early and often. If you get hung up on a problem, put it aside for awhile and work on another part of the project. As a mentor, I encourage students to follow up on methods and areas of research that is most successful in their hands [1]. In this way, students can find and build upon their strengths, while also achieving some level of immediate success. 


NOTES:
[1] This seems like a good place to plug the Orthogonal Research Lab's Open Career Development project. In particular, check out our laboratory contribution philosophy.

August 25, 2017

Live streaming of Orthogonal Lab content

Research live-streaming: an experiment in content [1].

The Orthogonal Research Laboratory, in conjunction with the OpenWorm Foundation, is starting to experiment with live video content. We are using YouTube Live, and live streams (composed in Xsplit Broadcaster) will be archived on the Orthogonal Lab YouTube channel. The intial forays into content will focus on research advances and collaborative meetings, but ideas for content are welcome. 




NOTES:

[1] obscure reference of the post: a shot of Felix the Cat, whose likeness was used to calibrate early experimental television broadcasts.

May 4, 2017

Announcing our Google Summer of Code 2017 Students


As mentioned in a previous post, the OpenWorm Foundation (and DevoWorm group) has been receiving application for this year's Google Summer of Code. We have now selected our student applicants and projects to be awarded the internship. We had a very good group of applicants this year, so congratulations go out to everyone who applied!


Shubham Singh will be working on the model completion dashboard project, which is a general tool for the OpenWorm community. Siddharth Yadav will be working with me and the rest of the DevoWorm group to quantify and analyze secondary microscopy data that capture the process of embryogenesis for C. elegans and other organisms [1]. Good luck!

Thanks to the INCF for coordinating the selection process!


NOTES: 
[1] For more reading on the promise of this approach, please see: Chi, K.R. (2017). Picking out Patterns. The Scientist, May 1 AND Rizvi, A.H., Camara, P.G., Kandror, E.K., Roberts, T.J., Schieren, I., Maniatis, T., and Rabadan, R. (2017). Single-cell topological rNA-seq analysis reveals insights into cellular differentiation and development. Nature Biotechnology, doi:10.1038/nbt.3854.

March 18, 2017

Almost time for GSoC Applications!

Your chance to join the DevoWorm group is almost upon us. If you are a student, the Google Summer of Code (GSoC) is a good opportunity to gain programming experience. Applications are being accepted from March 20 to April 3. If selected, you will join the DevoWorm group, and also have the chance to network with people from the OpenWorm Foundation and the INCF.

The best approach to a successful application is to discuss your skills, provide an outline of what you plan to do (which should resemble the project description), and then discuss your approach to solving the problems at hand. We are particularly interested in a demonstration of your problem-solving abilities, since many people will apply with a similar level of skill. You can find an application template in outline form here.


You can apply to work on one of two DevoWorm projects: "Physics-based Modeling of the Mosaic Embryo in CompuCell3D" or "Image processing with ImageJ (segmentation of high-resolution images)". If you have any questions, comment in the discussions or contact me directly.

February 8, 2017

Work With Me (and the OpenWorm Foundation) This Summer!

Want to work with me and contribute to the DevoWorm project this summer? Apply to work on a project funded through the Google Summer of Code (GSoC) fellowship​!



If you a student in the computational sciences and want to be challenged and get paid while working on an applied computer science project, then apply now to one of two projects [1, 2]. CSoC is a high profile fellowship, which provides a stipend, opportunities for professional collaboration, and an impressive line on your CV/resume. As I (Bradly Alicea) will serve as your mentor, please contact me if you have any questions.


Take ownership of an available cell! Apply to work with the DevoWorm project and OpenWorm Foundation!

You can apply to work on one of two DevoWorm projects: "Physics-based Modeling of the Mosaic Embryo in CompuCell3D" or "Image processing with ImageJ (segmentation of high-resolution images)". You may also apply to other projects sponsored by the OpenWorm Foundation and INCF.

UPDATE (3/8): Applications are being accepted starting March 20, 2017, and will close on April 3rd at 16:00 UTC.

September 23, 2016

Learning by Doing, Where Doing is Earning Badges

As a member of the OpenWorm Foundation community committee (see previous post), we have been trying to find a means of engaging potential contributors within the context of the various projects. One type of activity is the Badge, a bite-sized [1] learning opportunity that we plan to use as both certifications of competency and concrete goals for the various projects. The OpenWorm Badge System is being spearheaded by Chee-Wai Lee, and is an emerging method in Educational Technology [2]. More details about this will be shared to the community by Chee-Wai in the form of a tutorial at the upcoming OpenWorm Open House.

An example of how semantic data on phenotypes can be extracted from the scientific literature. PICTURE: Tagxedo.com, BLOGPOST: Phenoscape blog. 

Each badge is designed to impart a specific skill. The OpenWorm badge system currently covers scientific topics (Muscle Model Builder, Hodgkin-Huxley) and research skills (Literature Mining). My contribution is the Literature Mining (LM) series. Literature mining is a technique used to organize the scientific literature, extract useful metadata (e.g. semantic data) from these sources, and identify secondary datasets for re-analysis [3]. Learning skills in Literature Mining will be useful to a wide range of badge earners, particularly those interested in Bioinformatics and Open Science research. These are skills used extensively in the DevoWorm project, and we will be planning more badges on related topical areas in the future.

The first LM badge is focused on working with the scientific literature, while the second (LMII) badge introduces learners to open-access secondary datasets. The only prerequisite is that you must earn Badge I in order to earn Badge II. Both of these badges recently went live, and you may start working on them immediately.

Example of the badge curriculum for LMI. The badgelist system requires learners to complete each step one at a time, and then request feedback (if applicable) from the Admin (e.g. instructor).

NOTES:
[1] why not "byte-sized", you say? Well, the Literature Mining badges are almost byte-sized (seven requirements apiece), so you could say that we are headed in that direction!

[2] Ferdig, R. and Pytash, K. (2014).  There's a badge for that. Tech and Learning, February 26.

[3] For examples of how Literature Mining can be useful, please see the Nature site for news on literature mining research.

September 6, 2016

Now Announcing the OpenWorm Open House

OpenWorm Browser. Courtesy Christian Grove, WormBase and Caltech.

About two years ago, I announced the start of the DevoWorm project to the OpenWorm community. Now both OpenWorm and DevoWorm have grown up a bit, with the former (OpenWorm) now being a Foundation and the latter (DevoWorm) resulting in multiple publications. Now we will be celebrating all of the projects that make up the OpenWorm Foundation in an Open House format, taking place in cyberspace and tentatively scheduled for October.

Image courtesy Matteo Farinella: http://matteofarinella.com/Open-Worm. These posters are the outcome of an OpenWorm Kickstarter campaign several years ago.

The details of the schedule are still being worked out, but the format is to include both short, 5-minute talks (Ignite-style) and longer tutorials (45-60 minutes, plus questions). The short talks will highlight the various ongoing projects within OpenWorm, while the tutorials will focus on specific methods or procedures employed by the projects. If you happen to be a project leader or major contributor, I have probably already asked you for content. Interested in either contributing content or attending? Please let me know. 

Dr. Stephen Larson (pre-PhD), discussing the connection between Lt. Data and C. elegans at Ignite San Diego.

I have also been involved in committee work for the OpenWorm foundation. One of the initiatives we are in the process of establishing is the OpenWorm badge system, which is being spearheaded by Dr. Chee-Wai Lee. Currently trendy in the online learning world, this is an experiment in open learning that provides micro-credentials to a global community. Badges are a great way to learn new skills, as well as a means to motivate people's contributions to different projects within OpenWorm. Currently, OpenWorm is offering tutorials on the Hodgkin-Huxley model, the Muscle Model builder, and the Muscle Model explorer. If there are any tutorials you would like to see us offer, or if you think there is a need for a particular skill to be highlighted, please let me know.

February 12, 2016

Darwin Day, Past and Present

For this year's Darwin Day (his 207th posthumous birthday), we take a tour of Darwin Day features from both the past and present.

Panel discussion at the Darwin Centennial Celebration, University of Chicago circa 1959.

First stop: last year's Synthetic Daisies post for Darwin Day, featuring portraits of Charles Darwin throughout the course of his lifetime.

Second stop: 2009, and Nature's special issue for Darwin's 200th birthday, which includes many nice multimedia features.

Third stop: Google's Doodle from February 12, 2009 and  a Doodle-like short movie from 2014. Link to the Doodle design and animated movie can be found below. The movie is quite elaborate, as each letter making up "Google" are treated as terminal taxa in a prototypical tree of life.


Darwin Day Google Doodle from 2014. COURTESY: Vimeo and Devone Paul

Final stop: The Selfish Gene. This year's Darwin Day roughly coincides with the 40th anniversary of "The Selfish Gene" by Richard Dawkins. This work established the gene as the fundamental unit of natural selection, and provided a strong defense of Darwinian ideas. Enjoy these readings by John Brockman ("About Richard Dawkins") and Matt Ridley ("In Retrospect: The Selfish Gene").



Happy Darwin Day!

November 17, 2015

Lecture on Open Science, November 18!

I am presenting a lecture to the Webmasters Workshop series at UIUC tomorrow, November 18th. The title is "The Role of Web 2.0 Tools and Digital Practice in Doing Open Science". Physical location will be in the GSLIS Building, room 126 (501 E. Daniel). Virtual location (slideshow) is here. Virtual co-location (archived video) can be found here.

Please come if you are able! Here are some screenshots and takeaways from the presentation.






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